Research Groups

We firmly believe in sharing knowledge. From experienced veterans to talented young researchers, we work together in 62 groups.

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NKI

Reuven Agami Group

Controlling cancer by RNA

NKI

Leila Akkari Group

Immune cells and macrophages in therapeutically challenging tumors

NKI

René Bernards Group

Functional Cancer Genetics

Princess Máxima Center

Ruben van Boxtel Group

Cancer Etiology, Mutagenesis and Clonal Evolution

NKI

Thijn Brummelkamp Group

Experimental biomedical genetics

LUMC

Sjoerd van der Burg Group

Immunotherapy; T-cells; immune regulation; clinical trials

UMC Utrecht

Boudewijn Burgering Group

Signal transduction and metabolism

Erasmus MC

Miao-Ping Chien Group

Single cell technology, advanced imaging & quantitative analysis, cancer-driving cells, target discovery

Hubrecht Institute

Hans Clevers Group

Adult Stem cells and cancer

UMC Utrecht

Maria Rodriguez Colman Group

Metabolism, Cancer and Stem Cells

Erasmus MC

Ruud Delwel Group

Molecular genetics of AML

Amsterdam UMC

Sarah Derks Group

GEA, genome-immunome interactions, intratumor heterogeneity, targeted-immunotherapy

LUMC

Peter ten Dijke Group

Chemical Signaling

Princess Máxima Center

Jarno Drost Group

Molecular dissection of childhood solid tumors

Radboud UMC

Carl Figdor Group

Chemical Immunology, antigen presenting cells, Immunotherapy

UMCG

Lude Franke Group

Functional genomics

AMOLF

Kristina Ganzinger Group

Single-molecule imaging of immune receptor organisation & immune cell membrane models 

Amsterdam UMC

Joep Grootjans Group

The role of the immune system in cancer development and progression

Radboud University

Maike Hansen Group

Single Cell Analysis, Cell Fate Decisions 

Princess Máxima Center

Sebastiaan van Heesch Group

Microprotein biology and immunotherapy target discovery in childhood cancer

Leiden University

Laura Heitman Group

GPCR, allosteric modulation, target binding kinetics, small molecule

Princess Máxima Center

Jan Hoeijmakers Group

DNA repair

NKI

Jos Jonkers Group

Mouse models of breast cancer

Erasmus MC

Roland Kanaar Group

Molecular radiation biology

Hubrecht Institute

Jop Kind Group

Spatiotemporal regulation of genomic function

Hubrecht Institute

Puck Knipscheer Group

Molecular mechanisms and regulation of DNA repair

Hubrecht Institute

Geert Kops Group

Cell division & chromosome segregation

UMC Utrecht

Wouter de Laat Group

Biomedical genomics

UMC Utrecht

Susanne Lens Group

Genome instability

NKI

Tineke Lenstra Group

Transcription dynamics, single-molecule imaging

Radboud UMC

Geert Litjens Group

Applications of AI in oncology 

Erasmus MC

Jurgen Marteijn Group

Transcription Stress & Genome Stability

UMC Utrecht

Madelon Maurice Group

Mechanisms of cell-cell communication and tissue self-organization

Princess Máxima Center

René Medema Group

Cell Division and Cancer

Amsterdam UMC

Jan Paul Medema Group

Experimental Oncology and Radiobiology

UMC Utrecht

Linde Meyaard Group

Infection & immunity

LUMC

Jacques Neefjes Group

Cell biology, infection, cancer and cancer drugs

LUMC

Sylvie Noordermeer Group

DNA damage repair, homologous recombination, BRCA1

Hubrecht Institute

Alexander van Oudenaarden Group

Quantitative biology of development & stem cells

NKI

Daniel Peeper Group

Functional genomics for rational tumor and immune cell combination therapy

NKI

Anastassis Perrakis Group

Structural Biology, Cell Division, Lysolipid Signalling

Leiden University

Sebastian Pomplun Group

Drug discovery – Novel chemical modalities – Nucleic acid binding proteins

NKI

Jacco van Rheenen Group

Intravital Microscopy

UMC Utrecht

Jeroen de Ridder Group

Bioinformatics, Machine learning and AI, Nanopore Sequencing

Princess Máxima Center

Anne Rios Group

Cancer, immunotherapy development, high resolution 3D imaging, organoid technology, bio-engineering

Hubrecht Institute

Danny Sahtoe Group

Protein Design

Erasmus MC

Rebekka Schneider Group

Hematopoietic stem cells; leukemia; bone marrow failure; myelodysplastic syndrome; myeloproliferative neoplasms; genetic fate tracing; CRISPR-Cas9; scRNA sequencing

NKI

Ton Schumacher Group

Molecular Oncology & Immunology

NKI

Titia Sixma Group

Structural Biology

Princess Máxima Center

Hugo Snippert Group

Functional heterogeneity in cancer

NKI

Bas van Steensel Group

Genome Biology and Gene Regulation

Leiden University

Mario van der Stelt Group

Medicinal chemistry, drug discovery, chemical biology

Erasmus MC

Nitika Taneja Group

3-D chromatin remodeling and replication

Hubrecht Institute

Marvin Tanenbaum Group

Single molecule analysis of gene expression dynamics

NKI

Daniela Thommen Group

Precision cancer immunotherapy

Radboud University

Michiel Vermeulen Group

Proteomics & Chromatin biology

Amsterdam UMC

Louis Vermeulen Group

Cancer molecular subtypes, stem cell dynamics, colorectal cancer, microenvironment

NKI

Karin de Visser Group

Inflammation and cancer

NKI

Emile Voest Group

Genomics, precision medicine, organoids, immunotherapy

NKI

Lodewyk Wessels Group

Computational Biology

Sanquin

Monika Wolkers Group

T cell effector function, post-transcriptional gene regulation, RNA binding proteins

NKI

Wilbert Zwart Group

Hormones and Cancer