Jan Paul Medema
Awards
- 2009: Dutch Society of Gastroenterology Tytgat award
- 2007: VICI laureate of the Dutch Science Organization
- 2002: C.J.Kok prize
- 2000: VIDI laureate of the Dutch Science Organization
- 1996: Dutch Cancer Society Fellowship
- Honorary Professorship Brunel University London, UK
Key publications
- Ramesh, P., Di Franco, S., Atencia Taboada, L., Zhang, L.,…..& Medema, J.P. (2022). BCL-XL inhibition induces an FGFR4-mediated rescue response in colorectal cancer. Cell Reports, 38(7):110374.
- Ramesh, P., Lannagan, T.R.M., Jackstadt, R,, Atencia Taboada, L., Lansu, N.,….& Medema, J.P. (2021) BCL-XL is crucial for progression through the adenoma-to-carcinoma sequence of colorectal cancer. Cell Death Differentiation, 28(12):3282-3296.
- Linnekamp, J.F., Hooff, S.R.V., Prasetyanti, P.R., Kandimalla, R., Buikhuisen, J.Y.,…..& Medema JP. (2018)Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models. Cell Death Differentiation, 25(3):616-633.
- Guinney, J., Dienstmann, R., Wang, X., de Reyniès, A., Schlicker, A., …., Medema, J.P.* &….. Tejpar S.* (2015). The consensus molecular subtypes of colorectal cancer. Nature Medicine, 21(11):1350-6.
- Felipe De Sousa, E. M., Wang, X., Jansen, M., Fessler, E., Trinh, A., De Rooij, L. P., ... Medema J.P.* & Vermeulen, L.* (2013). Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions. Nature Medicine, 19(5), 614.
- Vermeulen, L., Felipe De Sousa, E. M., Van Der Heijden, M., Cameron, K., De Jong, J. H., Borovski, T., ... & Medema J.P. (2010). Wnt activity defines colon cancer stem cells and is regulated by the microenvironment. Nature Cell Biology, 12(5), 468.
- *shared senior authorships
Email address
Position
Oncode Investigator at AMC